I want to go ahead and say that when you do sign up, please use my referral link as I will get credit for your signing up. So, oDesk is a work-at-home bidding site where you bid on each assignment-- you're more or less competing with others for the same position (just like in the "real world," right!). It's very easy. No exaggeration there.
You read the employers job description and if you fit the bill, you click a button that says "apply" and you cater your cover letter to that employer and his special job posting. You don't even have to submit a resume!! Just make your cover letter really good and especially for that job posting so they know it's not generic.
Before any of this, you must create a profile and pass an "oDesk Readiness Test," with about 40 questions, which determines your level of seriousness about applying for jobs on oDesk.